Wanderers return to action in the Papa Johns Trophy knowing that victory will take them into the knock-out stages.
The Whites currently top Group B after a win and a draw in their opening two games.
A victory over Leeds would guarantee top spot and a home draw in the last 32.
The team that finishes second will also go through and Leeds currently hold that position after an opening night win at Tranmere, who have two points from two games thanks to the penalty shoot-out bonus point they secured against Wanderers.
Tranmere face Crewe in their final group game tonight, with Crewe looking for their first points after losing 4-1 at Wanderers in their first game.
A draw may also be enough for Wanderers to secure their passage through, depending on the result at Gresty Road with all games played over 90 minutes ahead of a penalty shoot-out for a bonus point if the scores are level.
Manager quotes:
Ian Evatt: "We want to get through and keep progressing from there and we know three points tonight will be enough to get us out of the group.
“I think out of all the young teams that enter this competition, they (Leeds) are probably the most senior group and they look to attack and progress.
“It will be a difficult game, but we will pay them huge respect and hopefully put an end to this mini drought that we are on and start scoring goals again.”
Team news
Wanderers are likely to make changes but still field a strong side as they look to advance to the knock-out phase.
Josh Sheehan and Lloyd Isgrove are expected to be among the starters as they press for a return to League One action.
Conor Bradley is available after picking up a fifth yellow card of the season in Saturday’s 0-0 draw against Barnsley, with his one-match ban kicking in for Saturday’s trip to Accrington Stanley.
Defender Eoin Toal has started the Whites’ first two games in the competition but misses out with a thigh injury.
Leeds included a couple of players with first-team experience in their opening group win at Tranmere.
Among them was former Wigan striker Joe Gelhardt, who scored twice in the 5-3 win.
However, Gelhardt (below) may be involved in United’s Premier League game at Leicester City on Thursday night after coming off the bench in Sunday’s loss to league leaders Arsenal.
Goalkeeper Kristoffer Klaesson is also set to feature against the Foxes so Harry Christy could return to face Wanderers.
Striker Sam Greenwood, who has also played Premier League football this season, is banned after being sent off in Leeds’ win at Tranmere in their last group game.
Form guide
Wanderers extended their unbeaten home run to five games in all competitions with Saturday’s 0-0 draw against Barnsley.
They have collected four points from their first two games in Group B of the Papa Johns Trophy.
The Whites – looking to end a three-games goalless run – reached the last-16 of the competition last season before going out at Hartlepool.
Leeds’ U21s started their Group B campaign with a 5-3 win at Tranmere.
The side coached by ex-England U18s’ boss Michael Skubala (above) has also started well in the second tier of Premier League 2 with six wins and a draw from seven games to top the table.
United’s youngsters have yet to get through the group stage of the Trophy after two previous seasons in the competition.
Officials
Referee: Peter Wright
Assistant referees: Joe Simpson and Simon Clayton
Fourth Official: David Richardson
Kick-off
Tuesday 7pm.
Coverage
Live streaming is available of the game with a video match pass available to buy for just £10 HERE
Fans can also access the matchday programme free by clicking HERE